Funded Postdoctoral Positions

We are currently seeking 4 Postdoctoral Research Associates to work with Professor Sir Shankar Balasubramanian on our Wellcome Trust and CRUK grants.

Previous applicants need not apply

2 x Postdoctoral Research Associates: Chemists/Chemical biologists to study DNA base modifications and their epigenetic functions (Fixed Term)

Fixed-term: The funds for this post are available for 2 years in the first instance.

We seek two postdoctoral scientists to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust-funded programme to investigate the structure and function of chemically modified nucleic acid bases. This is an interdisciplinary project that encompasses the use of organic and biophysical chemistry, chemical biology and molecular biology on DNA and on the genome.

We look to appoint chemists or chemical biologists to carry out research on how chemically modified bases affect the structure and function of DNA. The investigations will involve a consideration of the chemistry and enzymology of nucleic acids, protein-DNA interactions, epigenetics, chromatin structure and transcription. This will enable us to gain a deeper understanding of the function of base modifications and their involvement in regulating gene expression in normal and disease states using cellular models from human, and mouse and also parasite models.

The successful candidates will have a capacity for innovation and creativity. Strong communication skills and the ability to work effectively as part of a multi-disciplinary team will be important. Experience in nucleic acid chemistry and working in an interdisciplinary environment with molecular/cell biologists or biochemists would be an advantage.

Candidates should have (or be about to receive) a PhD in a relevant discipline. The positions are available immediately.

We can only consider applicants who apply through the University's online recruitment system via this link MA16981

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and your publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email: BalasubramanianRecruitment@ch.cam.ac.uk.

Please quote reference MA16981 on your application and in any correspondence about this vacancy.

Postdoctoral Research Associate: Molecular biologist/biochemist to explore DNA base modifications and their epigenetic functions (Fixed Term)

Fixed-term: The funds for this post are available for 2 years in the first instance.

We seek a postdoctoral scientist to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust-funded programme to investigate the epigenetic role of nucleic acid base modifications. This is an interdisciplinary project that encompasses chemical biology and molecular biology and genomics.

We look to appoint a molecular biologist or biochemist to carry out research on how chemically modified bases affect the structure and function of DNA. The investigations will involve a consideration of the chemistry and enzymology of modified bases, protein-DNA interactions, chromatin structure and transcription. We aim to manipulate the epigenetic states of systems as part of our studies. This will enable us to gain a deeper understanding of the function of base modifications and their involvement in regulating gene expression in normal and disease states using cellular models from human, and mouse and also parasite models.

The successful candidate will have a capacity for innovation and creativity. Strong communication skills and the ability to work effectively as part of a multi-disciplinary team will be important. Experience in working in an interdisciplinary environment, particularly with chemists/chemical biologists would be an advantage.

Candidates should have (or be about to receive) a PhD in a relevant discipline. The position is available immediately.

We can only consider applicants who apply through the University's online recruitment system via this link MA17561

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and your publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding applying online for this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email: BalasubramanianRecruitment@ch.cam.ac.uk

Please quote reference MA17561 on your application and in any correspondence about this vacancy.

Postdoctoral Research Associate: Chemist/chemical biologist (Fixed Term)

Fixed-term: The funds for this post are available for 2 years in the first instance.

Applications are invited for a talented postdoctoral chemist to work with Professor Sir Shankar Balasubramanian on the chemical biology of nucleic acids, funded by Cancer Research UK. The successful applicant will play a key role in an interdisciplinary project to develop and apply chemical tools to probe the fundamental structure, function and biological mechanisms of four-stranded DNA G-quadruplexes and to investigate their relevance as potential targets for therapeutic intervention and/or markers of cancer.

Applicants must have a background in organic chemistry and/or chemical biology, with strong interest in mechanisms associated with DNA function. Experience in biochemistry and in nucleic acid/protein interactions and transcriptional control would be highly desirable. We seek a highly-motivated individual with excellent communication skills and a capacity for innovation and creativity, who is able to work effectively as part of a multi-disciplinary team.

Candidates should have (or be about to receive) a PhD in a relevant discipline. The position is available immediately.

We can only consider applicants who apply through the University's online recruitment system via this link MA16982

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email: BalasubramanianRecruitment @ch.cam.ac.uk.

Please quote reference MA16982 on your application and in any correspondence about this vacancy.