Key Papers:
G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation
P Murat; J Zhong; L Lekieffre; N P Cowieson; J L Clancy; T Preiss; S Balasubramanian; R Khanna; J Tellam
Nature Chemical Biology, 2014, 10, 358–364
DOI:10.1038/nchembio.1479
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Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells
G Biffi; M Di Antonio; D Tannahill; S Balasubramanian
Nature Chemistry, 2014, 6, 75
DOI: 10.1038/nchem.1805
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Existence and consequences of G-quadruplex structures in DNA
P Murat; S Balasubramanian
Current Opinion in Genetics and Development, 2014, 25, 22-29
DOI: 10.1016/j.gde.2013.10.012
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Quantitative visualization of DNA G-quadruplex structures in human cells
G Biffi; D Tannahill; J McCafferty; S Balasubramanian
Nature Chemistry, 2013, 5, 182-186
DOI: 10.1038/nchem.1548
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Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry
M Di Antonio; G Biffi; A Mariani; E Raiber; R Rodriguez; S Balasubramanian
Angew. Chem. Int. Ed, 2012, 51 (44), 11073-11078
DOI: 10.1002/anie.201206281
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5′-UTR RNA G-quadruplexes: translation regulation and targeting
A Bugaut; S Balasubramanian
Nucleic Acids Research, 2012, 40 (11), 4727-4741
DOI: 10.1093/nar/gks068
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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
R Rodriguez; K M Miller; J V Forment; C R Bradshaw; M Nikan; S Britton; T Oelschlaegel; B Xhemalce; S Balasubramanian; S P Jackson
Nat. Chem. Biol., 2012, 8 (3), 301-10
DOI: 10.1038/nchembio.780
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Targeting G‐quadruplexes in gene promoters: a novel anticancer strategy?
S Balasubramanian, L H Hurley and S Neidle
Nature Reviews Drug Discovery, 2011, 10, 261-275
DOI:10.1038/nrd3428
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A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics
S T Hsu, P Varnai, A Bugaut, A P Reszka, S Neidle and S Balasubramanian
J. Am. Chem. Soc., 2009, 131, 13399-409
DOI: 10.1021/ja904007p
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G-quadruplex nucleic acids as therapeutic targets
S Balasubramanian and S Neidle
Current Opinion in Chemical Biology, 2009, 13, 345-353
DOI: 10.1016/j.cbpa.2009.04.637
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An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation
S Kumari; A Bugaut; J L Huppert; S Balasubramanian
Nature Chem. Biol., 2007, 3, 218-221
DOI: 10.1038/nchembio864
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Prevalence of quadruplexes in the human genome
J L Huppert; S Balasubramanian
Nucleic Acids Res., 2005, 33, 2908-2916
DOI: 10.1093/nar/gki609
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